Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2- and RIPK1/RIP1-mediated MAPK8/JNK activation

Weiyang He, Qiong Wang, Jennings Xu, +5

Autophagy

MitophagyRipk1/rip1-mediated Mapk8/jnk ActivationApoptosisImmunologyCell Death +16

DNA methylation downregulated ZDHHC1 suppresses tumor growth by altering cellular metabolism and inducing oxidative/ER stress-mediated apoptosis and pyroptosis

Le Xin, Junhao Mu, Weiyan Peng, +11

Theranostics

17-Allylamino-17-Demethoxygeldanamycin Synergistically Potentiates Tumor Necrosis Factor–Induced Lung Cancer Cell Death by Blocking the Nuclear Factor-κB Pathway

Xia Wang, Wei Ju, Jordan J. Renouard, +3

Cancer Research

c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly(ADP-ribose) polymerase-1 activation

Siyuan Zhang, Yong Lin, YS Kim, +3

Cell Death and Differentiation

Polymerase-1 ActivationRedox SignalingCell RegulationLipid PeroxidationApoptosis +9

ROS activates JNK-mediated autophagy to counteract apoptosis in mouse mesenchymal stem cells in vitro

Liu Guanyu, Xiaoxue Jiang, Xin Zhu, +5

Acta Pharmacologica Sinica

Regenerative MedicineCell AutophagyMitophagyDevelopmental BiologyMedicine +9

RIP1 potentiates BPDE-induced transformation in human bronchial epithelial cells through catalase-mediated suppression of excessive reactive oxygen species

Qiong Wang, Wenshu Chen, Xiuling Xu, +8

Carcinogenesis

Bpde-induced TransformationCell DeathCancer BiologyTumor BiologyOxidative Stress +16

Epidermal Growth Factor Receptor-mediated Tissue Transglutaminase Overexpression Couples Acquired Tumor Necrosis Factor-related Apoptosis-inducing Ligand Resistance and Migration through c-FLIP and MMP-9 Proteins in Lung Cancer Cells

Zi Li, Xiuling Xu, Lang Bai, +2

Journal of Biological Chemistry

Cancer ResearchMmp-9 ProteinsMedicineApoptosisImmunology +12

Glucose up‐regulates HIF‐1α expression in primary cortical neurons in response to hypoxia through maintaining cellular redox status

Shuhong Guo, Olga Bragina, Yuexian Xu, +8

Journal of Neurochemistry

A HIF-1 Target, ATIA, Protects Cells from Apoptosis by Modulating the Mitochondrial Thioredoxin, TRX2

Swati Choksi, Yong Lin, Li Chen, +12

Molecular Cell

MitophagySignal TransductionMitochondrial FunctionCell SignalingApoptosis +10

Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity

Jun-Ho Jang, Shannon Bruse, Yushi Liu, +10

Free Radical Biology and Medicine

Tobacco ControlAldehyde DehydrogenaseBiochemistryRespiratory ToxicologyNicotine +11