Joan Marsh

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

Emma Hockly, Victoria M. Richon, Benjamin Woodman et al. · Proceedings of the National Academy of Sciences · 2003 · 836 citations · Full text

SUMO Modification of Huntingtin and Huntington's Disease Pathology

Joan S. Steffan, Namita Agrawal, Judit Pallos et al. · Science · 2004 · 704 citations · Full text

β-catenin–sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer

Karine Hovanes, Tony W.H. Li, Jesus E. Munguia et al. · Nature Genetics · 2001 · 463 citations

Tumor Biology, Gastrointestinal Oncology, Medicine +11

Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models

Dagmar E. Ehrnhoefer, Martin L. Duennwald, Phoebe Markovic et al. · Human Molecular Genetics · 2006 · 413 citations · Full text

Hd Flies, Green Tea Polyphenol, Genetics +18

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

Leslie M. Thompson, Charity T. Aiken, Linda S. Kaltenbach et al. · The Journal of Cell Biology · 2009 · 388 citations · Full text

Polyglutamine Repeat, Proteasome, Molecular Biology +19