Zhen‐Yong Wang

Autophagy blockade and lysosomal membrane permeabilization contribute to lead-induced nephrotoxicity in primary rat proximal tubular cells

Xiang-Bin Song, Gang Liu, Fei Liu et al. · Cell Death and Disease · 2017 · 186 citations · Full text

Life Sciences, Pharmacology, Toxicology +17

Epigenetic regulator BRD4 is involved in cadmium-induced acute kidney injury via contributing to lysosomal dysfunction, autophagy blockade and oxidative stress

Zhonggui Gong, Yuan Zhao, Zhen‐Yong Wang et al. · Journal of Hazardous Materials · 2021 · 151 citations

Life Sciences, Cell Biology, Molecular Biology +15

Cadmium disrupts autophagic flux by inhibiting cytosolic Ca2+-dependent autophagosome-lysosome fusion in primary rat proximal tubular cells

Fei Liu, Xinyu Wang, Xuping Zhou et al. · Toxicology · 2017 · 128 citations

Life Sciences, Cell Biology, Physiology +17

Trehalose protects against cadmium-induced cytotoxicity in primary rat proximal tubular cells via inhibiting apoptosis and restoring autophagic flux

Xinyu Wang, Heng Yang, Min-Ge Wang et al. · Cell Death and Disease · 2017 · 121 citations · Full text

Life Sciences, Cell Biology, Toxicology +17

Persistent activation of Nrf2 in a p62-dependent non-canonical manner aggravates lead-induced kidney injury by promoting apoptosis and inhibiting autophagy

Cai-Yu Lian, Bingxin Chu, Wei-Hao Xia et al. · Journal of Advanced Research · 2022 · 110 citations · Full text

Pharmacy, Cell Biology, Toxicology +17