Yin Guo

Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Yunhang Guo, Ye Liu, Nan Hu et al. · Journal of Medicinal Chemistry · 2019 · 349 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Dopamine D₂‐like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP‐protein kinase A and NMDA receptor signaling

Jianhong Li, Yin Guo, Frederick A. Schroeder et al. · Journal of Neurochemistry · 2004 · 150 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Chromatin Alterations Associated With Down-regulated Metabolic Gene Expression in the Prefrontal Cortex of Subjects With Schizophrenia

Schahram Akbarian, Martin Ruehl, Erin E. Bliven et al. · Archives of General Psychiatry · 2005 · 141 citations

Life Sciences, Genetics, Molecular Biology +17

Neuroinflammation and α-synuclein accumulation in response to glucocerebrosidase deficiency are accompanied by synaptic dysfunction

Edward I. Ginns, Sally K. Mak, Novie Ko et al. · Molecular Genetics and Metabolism · 2013 · 107 citations

Life Sciences, Neurobiology, Neuroscience +14

Pamiparib is a potent and selective PARP inhibitor with unique potential for the treatment of brain tumor

Yao Xiong, Yin Guo, Ye Liu et al. · Neoplasia · 2020 · 98 citations · Full text

Medicine, Oncology, Pharmacology +17