Yong-Jun Huang

Design and Synthesis of 3-Hydroxy-pyridin-4(1 <i>H</i> )-ones–Ciprofloxacin Conjugates as Dual Antibacterial and Antibiofilm Agents against <i>Pseudomonas aeruginosa</i>

Yuan‐Yuan Wang, Xiaoyi Zhang, Xiaolin Zhong et al. · Journal of Medicinal Chemistry · 2023 · 34 citations

Discovery of the First Examples of Threonine Tyrosine Kinase PROTAC Degraders

Jibu Lu, Yong-Jun Huang, Jing Huang et al. · Journal of Medicinal Chemistry · 2022 · 23 citations · Full text

3-Hydroxy-pyridin-4(1H)-ones as siderophores mediated delivery of isobavachalcone enhances antibacterial activity against pathogenic Pseudomonas aeruginosa

Yong-Jun Huang, Xiaolin Zhong, Yi-Peng Zang et al. · European Journal of Medicinal Chemistry · 2023 · 20 citations

Antimicrobial Susceptibility, Antibiotics, Pathogenic Pseudomonas Aeruginosa +7

3-Hydroxypyridin-4(1<i>H</i>)-one Derivatives as <i>pqs</i> Quorum Sensing Inhibitors Attenuate Virulence and Reduce Antibiotic Resistance in <i>Pseudomonas aeruginosa</i>

Zhiying Miao, Xiaoyi Zhang, Ming-Han Yang et al. · Journal of Medicinal Chemistry · 2023 · 18 citations

Excellent Antivirulence Properties, Microbial Pathogens, Antibiotic Adjuvant +23