Huanzhang Xie

Pharmacophore modeling studies of type I and type II kinase inhibitors of Tie2

Qingqing Xie, Huanzhang Xie, Ji-Xia Ren et al. · Journal of Molecular Graphics and Modelling · 2008 · 114 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

SKLB1002, a Novel Potent Inhibitor of VEGF Receptor 2 Signaling, Inhibits Angiogenesis and Tumor Growth <i>In Vivo</i>

Shuang Zhang, Zhixing Cao, Hongwei Tian et al. · Clinical Cancer Research · 2011 · 101 citations

Medicine, Oncology, Pharmacology +15

PocketFlow is a data-and-knowledge-driven structure-based molecular generative model

Yuanyuan Jiang, Guo Zhang, Jing You et al. · Nature Machine Intelligence · 2024 · 88 citations

Life Sciences, Bioinformatics, Chemistry +12

Towards more accurate pharmacophore modeling: Multicomplex-based comprehensive pharmacophore map and most-frequent-feature pharmacophore model of CDK2

Jun Zou, Huanzhang Xie, Shengyong Yang et al. · Journal of Molecular Graphics and Modelling · 2008 · 73 citations

Pharmacy, Chemical Biology, Medicinal Chemistry +16

Discovery of Novel Pim-1 Kinase Inhibitors by a Hierarchical Multistage Virtual Screening Approach Based on SVM Model, Pharmacophore, and Molecular Docking

Ji-Xia Ren, Linli Li, Renlin Zheng et al. · Journal of Chemical Information and Modeling · 2011 · 73 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17