Shizuo Machida

Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy

Dongdong Wang, Yasushi Saga, Hiroaki Mizukami et al. · International Journal of Oncology · 2011 · 72 citations · Full text

Medicine, Immunology, Oncology +14

Indoleamine 2,3-dioxygenase promotes peritoneal dissemination of ovarian cancer through inhibition of natural killercell function and angiogenesis promotion.

Hiroaki Nonaka, Yasushi Saga, Hiroyuki Fujiwara et al. · PubMed · 2011 · 50 citations

Medicine, Oncology, Pharmacology +13

<i>In vivo</i> delivery of si<scp>RNA</scp> targeting vasohibin‐2 decreases tumor angiogenesis and suppresses tumor growth in ovarian cancer

Takahiro Koyanagi, Yasuhiro Suzuki, Yasushi Saga et al. · Cancer Science · 2013 · 45 citations · Full text

Medicine, Oncology, Pharmacology +17

Downregulation of indoleamine-2,3-dioxygenase in cervical cancer cells suppresses tumor growth by promoting natural killer cell accumulation

Naoto Sato, Yasushi Saga, Hiroaki Mizukami et al. · Oncology Reports · 2012 · 45 citations · Full text

Medicine, Immunology, Oncology +13

Inhibition of peritoneal dissemination of ovarian cancer by tyrosine kinase receptor inhibitor SU6668 (TSU‐68)

Shizuo Machida, Yasushi Saga, Yuji Takei et al. · International Journal of Cancer · 2004 · 42 citations · Full text

Medicine, Oncology, Pharmacology +17