Micelle‐Based Brain‐Targeted Drug Delivery Enabled by a Nicotine Acetylcholine Receptor Ligand

Changyou Zhan, Bian Li, Luojuan Hu, +4

Angewandte Chemie International Edition

Candid CandoxinDrug TargetingBlood–brain BarrierMedicineNicotine +11

Transferrin-conjugated polyphosphoester hybrid micelle loading paclitaxel for brain-targeting delivery: Synthesis, preparation and in vivo evaluation

Pengcheng Zhang, Luojuan Hu, Qi Yin, +3

Journal of Controlled Release

NanomedicineMedicinal ChemistryDrug TargetingEngineeringPolymer-drug Conjugate +9

Transferrin-Modified c[RGDfK]-Paclitaxel Loaded Hybrid Micelle for Sequential Blood-Brain Barrier Penetration and Glioma Targeting Therapy

Pengcheng Zhang, Luojuan Hu, Qi Yin, +2

Molecular Pharmaceutics

Effective ChemotherapyNanomedicineNeuro-oncologyGlioma Targeting TherapyGlioma Chemotherapy +12

Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential treatment target in obesity

Enyuan Cao, Matthew J. Watt, Cameron J. Nowell, +20

Nature Metabolism

ObesityMetabolic SyndromeBody CompositionPotential Treatment TargetDiabetes +8

Targeted delivery of a model immunomodulator to the lymphatic system: Comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies

Sifei Han, Tim Quach, Luojuan Hu, +6

Journal of Controlled Release

Cell-based Drug DeliveryLipid PreparationMedicineImmunologyModel Immunomodulator +5

Glyceride‐Mimetic Prodrugs Incorporating Self‐Immolative Spacers Promote Lymphatic Transport, Avoid First‐Pass Metabolism, and Enhance Oral Bioavailability

Luojuan Hu, Tim Quach, Sifei Han, +6

Angewandte Chemie International Edition

Poly(ε-caprolactone)-Block-poly(ethyl Ethylene Phosphate) Micelles for Brain-Targeting Drug Delivery: In Vitro and In Vivo Valuation

Pengcheng Zhang, Luojuan Hu, Yucai Wang, +3

Pharmaceutical Research

NanomedicineEngineeringPolymer-drug ConjugateMedicinePolymer Science +9

The Mesenteric Lymph Duct Cannulated Rat Model: Application to the Assessment of Intestinal Lymphatic Drug Transport

Natalie L. Trevaskis, Luojuan Hu, Suzanne M. Caliph, +2

Journal of Visualized Experiments

Gastrointestinal PharmacologyImmunologyGastroenterologyDigestive TractImmune System +14

Profiling the Role of Deacylation-Reacylation in the Lymphatic Transport of a Triglyceride-Mimetic Prodrug

Sifei Han, Luojuan Hu, Tim Quach, +3

Pharmaceutical Research

BiochemistryLymphatic TransportTriglyceride-mimetic ProdrugLipid MovementPharmacology +1

Lymphatic Transport and Lymphocyte Targeting of a Triglyceride Mimetic Prodrug Is Enhanced in a Large Animal Model: Studies in Greyhound Dogs

Sifei Han, Luojuan Hu, Gracia, +5

Molecular Pharmaceutics

Lymphatic TransportImmunologyHigher Order SpeciesPharmacotherapyInflammation +14