Mototsugu Yamada

OP0595, a new diazabicyclooctane: mode of action as a serine β-lactamase inhibitor, antibiotic and β-lactam ‘enhancer’

Akihiro Morinaka, Yuko Tsutsumi, Mototsugu Yamada et al. · Journal of Antimicrobial Chemotherapy · 2015 · 161 citations · Full text

Phenylimidazole Derivatives of 4-Pyridone as Dual Inhibitors of Bacterial Enoyl-Acyl Carrier Protein Reductases FabI and FabK

Hideo Kitagawa, Tomohiro Ozawa, Sho Takahata et al. · Journal of Medicinal Chemistry · 2007 · 62 citations · Full text

Crystal structure of enoyl–acyl carrier protein reductase (FabK) from <i>Streptococcus pneumoniae</i> reveals the binding mode of an inhibitor

Jun Saito, Mototsugu Yamada, Takashi Watanabe et al. · Protein Science · 2008 · 56 citations · Full text

Crystal Structure of Cefditoren Complexed with <i>Streptococcus pneumoniae</i> Penicillin-Binding Protein 2X: Structural Basis for Its High Antimicrobial Activity

Mototsugu Yamada, Takashi Watanabe, Takako Miyara et al. · Antimicrobial Agents and Chemotherapy · 2007 · 45 citations · Full text

Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from <i>Streptococcus pneumoniae</i>

Mototsugu Yamada, Takashi Watanabe, Nobuyoshi Baba et al. · Antimicrobial Agents and Chemotherapy · 2008 · 43 citations · Full text

Crystal Structure, Penicillin-binding Proteins 2X, Molecular Biology +16