The effect of P-glycoprotein on paclitaxel brain and brain tumor distribution in mice.

James M. Gallo, Shaolan Li, Ping Guo, +2

PubMed

Neuro-oncologyTumor BiologyTumor InnervationPaclitaxel BrainPgp Knockout Mice +13

Pharmacodynamic-Mediated Effects of the Angiogenesis Inhibitor SU5416 on the Tumor Disposition of Temozolomide in Subcutaneous and Intracerebral Glioma Xenograft Models

Jianguo Ma, Shaolan Li, Karin Reed, +2

Journal of Pharmacology and Experimental Therapeutics

Synergistic cytotoxicity of cisplatin and topotecan or SN-38 in a panel of eight solid-tumor cell lines in vitro

Jianguo Ma, Marc Maliepaard, Kees Nooter, +4

Cancer Chemotherapy and Pharmacology

Tumor BiologyMedicinePharmacologyAnti-cancer AgentCancer Treatment +5

Comparison of ethanol plasma-protein precipitation with plasma ultrafiltration and trichloroacetic acid protein precipitation for the measurement of unbound platinum concentrations

Jianguo Ma, G. Stoter, Jaap Verweij, +1

Cancer Chemotherapy and Pharmacology

Unbound Platinum ConcentrationsEngineeringBiochemistryBioanalysisAnalytical Chemistry +7

Biochemical changes associated with a multidrug-resistant phenotype of a human glioma cell line with temozolomide-acquired resistance

Jianguo Ma, Maureen E. Murphy, Peter J. O’Dwyer, +3

Biochemical Pharmacology

Temozolomide-acquired ResistanceBiochemical ChangesDrug Resistance AnalysisMedicineMultidrug-resistant Phenotype +7

Pharmacokinetic Model-Predicted Anticancer Drug Concentrations in Human Tumors

James M. Gallo, Paolo Vicini, Amy Orlansky, +6

Clinical Cancer Research

Determination of paclitaxel in mouse plasma and brain tissue by liquid chromatography–mass spectrometry

Ping Guo, Jianguo Ma, Shaolan Li, +1

Journal of Chromatography B

Molecular PharmacologyLiquid Chromatography–mass SpectrometryPharmacological StudyMedicineMouse Plasma +7

MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models

Francesca Vena, Ruochen Jia, Arman Esfandiari, +9

Oncotarget

Targeted delivery of a peripheral benzodiazepine receptor ligand-gemcitabine conjugate to brain tumors in a xenograft model

Ping Guo, Jianguo Ma, Shaolan Li, +3

Cancer Chemotherapy and Pharmacology

Neuro-oncologyDrug TargetingGliomaMedicineTheranostics +9

Abrogated energy-dependent uptake of cisplatin in a cisplatin-resistant subline of the human ovarian cancer cell line IGROV-1

Jianguo Ma, Marc Maliepaard, Herman J. Kolker, +2

Cancer Chemotherapy and Pharmacology

Energy-dependent UptakeOncologyOncogenic AgentMedicineCancer Biology +9