Ruotong Ren

A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging

Weiqi Zhang, Jingyi Li, Keiichiro Suzuki et al. · Science · 2015 · 534 citations · Full text

SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2

Huize Pan, Di Guan, Xiaomeng Liu et al. · Cell Research · 2016 · 330 citations · Full text

SIRT6 deficiency results in developmental retardation in cynomolgus monkeys

Weiqi Zhang, Haifeng Wan, Guihai Feng et al. · Nature · 2018 · 202 citations

Developmental Biology, Genetic Disorder, Developmental Genetics +5

Targeted Gene Correction Minimally Impacts Whole-Genome Mutational Load in Human-Disease-Specific Induced Pluripotent Stem Cell Clones

Keiichiro Suzuki, Chang Yu, Jing Qu et al. · Cell stem cell · 2014 · 172 citations · Full text

Induced Pluripotent Stem Cell, Medicine, Genetics +9

PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype

Shunlei Duan, Guohong Yuan, Xiaomeng Liu et al. · Nature Communications · 2015 · 166 citations · Full text