Qun-Wei Lu

Knock-In Mouse Model of Dilated Cardiomyopathy Caused by Troponin Mutation

Cheng-Kun Du, Sachio Morimoto, Kiyomasa Nishii et al. · Circulation Research · 2007 · 180 citations

Life Sciences, Cardiology, Genetics +17

Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T–tropomyosin interaction and causes a Ca2+ desensitization

Qun-Wei Lu, Sachio Morimoto, Keita Harada et al. · Journal of Molecular and Cellular Cardiology · 2003 · 99 citations

Life Sciences, Cardiology, Molecular Biology +14

Functional Consequences of the Mutations in Human Cardiac Troponin I Gene Found in Familial Hypertrophic Cardiomyopathy

Fumi Takahashi‐Yanaga, Sachio Morimoto, Keita Harada et al. · Journal of Molecular and Cellular Cardiology · 2001 · 92 citations

Medicine, Cardiology, Genetics +13

Drastic Ca2+ sensitization of myofilament associated with a small structural change in troponin I in inherited restrictive cardiomyopathy

Fumiaki Yumoto, Qun-Wei Lu, Sachio Morimoto et al. · Biochemical and Biophysical Research Communications · 2005 · 86 citations

Medicine, Biophysics, Cardiology +11

Targeted disruption of the cardiac troponin T gene causes sarcomere disassembly and defects in heartbeat within the early mouse embryo

Kiyomasa Nishii, Sachio Morimoto, Reiko Minakami et al. · Developmental Biology · 2008 · 76 citations

Life Sciences, Genetics, Molecular Biology +10