Xuezhi Dai

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22

Marianne R. Spalinger, Stephanie Kasper, Claudia Gottier et al. · Journal of Clinical Investigation · 2016 · 225 citations · Full text

Chronic Inflammatory Diseases, Molecular Regulation, Immune Regulation +31

A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models

Xuezhi Dai, Richard G. James, Tania Habib et al. · Journal of Clinical Investigation · 2013 · 179 citations · Full text

Disease-associated Ptpn22 Variant, T-regulatory Cell, Graves Disease +20

The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity

Jacquelyn A. Gorman, Christian Hundhausen, John S. Errett et al. · Nature Immunology · 2017 · 136 citations · Full text

Interferon Program, Autoimmune Disease, A946t Variant +9

PTPN22 regulates NLRP3-mediated IL1B secretion in an autophagy-dependent manner

Marianne R. Spalinger, Silvia Lang, Claudia Gottier et al. · Autophagy · 2017 · 122 citations · Full text

Inflammation, Gene Locus, Cell Autophagy +14

Altered B Cell Homeostasis Is Associated with Type I Diabetes and Carriers of the PTPN22 Allelic Variant

Tania Habib, Andrew Funk, Mary Rieck et al. · The Journal of Immunology · 2011 · 119 citations · Full text

Ptpn22 Allelic Variant, T-regulatory Cell, Immunology +17