Xun Cai

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells.

Guoqiang Chen, Xuegeng Shi, Wei Tang et al. · PubMed · 1997 · 803 citations

Medicine, Hematology, Oncology +14

Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia

Xun Cai, Y-L Shen, Qian Zhu et al. · Leukemia · 2000 · 261 citations

Life Sciences, Cell Biology, Oncology +17

Gain-of-function mutation of <i>GATA-2</i> in acute myeloid transformation of chronic myeloid leukemia

Sujiang Zhang, Liyuan Ma, Qiuhua Huang et al. · Proceedings of the National Academy of Sciences · 2008 · 180 citations · Full text

Medicine, Genetics, Hematology +13

Synergic effects of arsenic trioxide and cAMP during acute promyelocytic leukemia cell maturation subtends a novel signaling cross-talk

Qi Zhu, Jiwang Zhang, Haiqing Zhu et al. · Blood · 2002 · 86 citations

Life Sciences, Cell Biology, Molecular Biology +13

Arsenic trioxide-induced mitotic arrest and apoptosis in acute promyelocytic leukemia cells

Xun Cai, Yanbao Yu, Yahui Huang et al. · Leukemia · 2003 · 73 citations

Life Sciences, Cell Biology, Oncology +14