MicroRNA-26a negatively regulates toll-like receptor 3 expression of rat macrophages and ameliorates pristane induced arthritis in rats

Congshan Jiang, Wenhua Zhu, Jing Xu, +10

Arthritis Research & Therapy

Down‐regulation of miR‐10a‐5p in synoviocytes contributes to TBX5‐controlled joint inflammation

Nazim Hussain, Wenhua Zhu, Congshan Jiang, +10

Journal of Cellular and Molecular Medicine

Reactive oxygen species regulation by NCF1 governs ferroptosis susceptibility of Kupffer cells to MASH

Jing Zhang, Yu Wang, Meiyang Fan, +17

Cell Metabolism

Reductive StressSignal TransductionNcf1 GovernsBiochemistryReactive Nitrogen Specie +10

Synthesis and anticancer activity evaluation of a series of [1,2,4]triazolo[1,5-a]pyridinylpyridines in vitro and in vivo

Xiaomeng Wang, Jing Xu, Yiping Li, +5

European Journal of Medicinal Chemistry

Medicinal ChemistryMedicineOrganic ChemistryAnticancer Activity EvaluationAnti-cancer Agent +6

A novel matrine derivate inhibits differentiated human hepatoma cells and hepatic cancer stem-like cells by suppressing PI3K/AKT signaling pathways

Ying Liu, Qi Yang, Zhi-Hui Bai, +9

Acta Pharmacologica Sinica

Upregulated PKM2 in Macrophages Exacerbates Experimental Arthritis via STAT1 Signaling

Jing Xu, Congshan Jiang, Xipeng Wang, +12

The Journal of Immunology

ImmunologyInflammatory ArthritisInflammationRheumatoid DisorderInflammatory Rheumatic Disease +14

Synthesis and antitumor activities evaluation of m-(4-morpholinoquinazolin-2-yl)benzamides in vitro and in vivo

Xiaomeng Wang, Minhang Xin, Jing Xu, +4

European Journal of Medicinal Chemistry

Medicinal ChemistryPharmaceutical ScienceAntitumor Activities EvaluationMedicinePharmacological Agent +8

Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumatoid arthritis synoviocytes

Jing Xu, Congshan Jiang, Yongsong Cai, +14

Arthritis Research & Therapy

Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis

Yuanxu Guo, Zixin Min, Congshan Jiang, +16

Cell Death and Disease

Gene deficiency or pharmacological inhibition of PDCD4-mediated FGR signaling protects against acute kidney injury

Jing Xu, Dandan Ren, Fei Gao, +8

Acta Pharmaceutica Sinica B