Xiaolei Chen

IL-1β receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes

Fen Wang, Jijie Liu, Xiaolei Chen et al. · Arthritis Research & Therapy · 2019 · 54 citations · Full text

Chondroprotection of PPARα activation by WY14643 via autophagy involving Akt and ERK in LPS‐treated mouse chondrocytes and osteoarthritis model

Yang Zhou, Xiaolei Chen, Ning Qu et al. · Journal of Cellular and Molecular Medicine · 2019 · 32 citations · Full text

Phosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells

Lianzhi Dai, Xiaolei Chen, Xiaohong Lü et al. · Scientific Reports · 2017 · 27 citations · Full text

Nintedanib ameliorates osteoarthritis in mice by inhibiting synovial inflammation and fibrosis caused by <scp>M1</scp> polarization of synovial macrophages via the <scp>MAPK</scp> / <scp>PI3K‐AKT</scp> pathway

Jiangbo Yan, Gangning Feng, Yong Yang et al. · The FASEB Journal · 2023 · 25 citations · Full text

PLCγ1 inhibition‐driven autophagy of IL‐1β‐treated chondrocyte confers cartilage protection against osteoarthritis, involving AMPK, Erk and Akt

Xiaolei Chen, Yue Wang, Ning Qu et al. · Journal of Cellular and Molecular Medicine · 2020 · 20 citations · Full text