Xiaolei Chen

IL-1β receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes

Fen Wang, Jijie Liu, Xiaolei Chen et al. · Arthritis Research & Therapy · 2019 · 56 citations · Full text

Life Sciences, Orthopedic Surgery, Pharmacology +17

Chondroprotection of PPARα activation by WY14643 via autophagy involving Akt and ERK in LPS‐treated mouse chondrocytes and osteoarthritis model

Yang Zhou, Xiaolei Chen, Ning Qu et al. · Journal of Cellular and Molecular Medicine · 2019 · 33 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

DAG/PKCδ and IP3/Ca2+/CaMK IIβ Operate in Parallel to Each Other in PLCγ1-Driven Cell Proliferation and Migration of Human Gastric Adenocarcinoma Cells, through Akt/mTOR/S6 Pathway

Lianzhi Dai, Luhua Zhuang, Bingchang Zhang et al. · International Journal of Molecular Sciences · 2015 · 28 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Nintedanib ameliorates osteoarthritis in mice by inhibiting synovial inflammation and fibrosis caused by <scp>M1</scp> polarization of synovial macrophages via the <scp>MAPK</scp> / <scp>PI3K‐AKT</scp> pathway

Jiangbo Yan, Gangning Feng, Yong Yang et al. · The FASEB Journal · 2023 · 28 citations · Full text

Medicine, Orthopaedic Surgery, Pharmacology +17

Phosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells

Lianzhi Dai, Xiaolei Chen, Xiaohong Lü et al. · Scientific Reports · 2017 · 27 citations · Full text

Life Sciences, Cell Biology, Oncology +17