NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development

Woo‐Young Kim, Bernd Fritzsch, Amanda E. Serls, +5

Development

Severe LossDeath AssaysAuditory ScienceNeurod-null MiceCell Signaling +18

Intrinsic Transcriptional Activation-Inhibition Domains of the Polyomavirus Enhancer Binding Protein 2/Core Binding Factor α Subunit Revealed in the Presence of the β Subunit

Tomohiko Kanno, Yuka Kanno, Lin‐Feng Chen, +3

Molecular and Cellular Biology

Negative regulation of granulocytic differentiation in the myeloid precursor cell line 32Dcl3 by<i>ear</i>-2, a mammalian homolog of<i>Drosophila seven-up</i>, and a chimeric leukemogenic gene,<i>AML1/ETO</i>(<i>MTG8</i>)

Mee‐Young Ahn, Gang Huang, Suk‐Chul Bae, +3

Proceedings of the National Academy of Sciences

Clinical and biochemical relevance of monounsaturated fatty acid metabolism targeting strategy for cancer stem cell elimination in colon cancer

SeokGyeong Choi, Young Ji Yoo, Hyejin Kim, +7

Biochemical and Biophysical Research Communications

Chemoprevention StrategyOmega-3 Fatty AcidMedicineColorectal CancerBiochemical Relevance +6

Evodiamine Eliminates Colon Cancer Stem Cells via Suppressing Notch and Wnt Signaling

Hyejin Kim, Yeongji Yu, SeokGyeong Choi, +4

Molecules

Cancer Stem CellWnt SignalingCancer BiologyTumor BiologyAnti-cancer Agent +16

Targeting a Lipid Desaturation Enzyme, SCD1, Selectively Eliminates Colon Cancer Stem Cells through the Suppression of Wnt and NOTCH Signaling

Yeongji Yu, Hyejin Kim, SeokGyeong Choi, +5

Cells

Chemoprevention StrategyCancer Stem CellApoptosisImmunologyCell Death +16

FBXW7-mediated stability regulation of signal transducer and activator of transcription 2 in melanoma formation

Cheol‐Jung Lee, Hyun‐Jung An, Seung Min Kim, +10

Proceedings of the National Academy of Sciences

Systemic Approaches Identify a Garlic-Derived Chemical, Z-ajoene, as a Glioblastoma Multiforme Cancer Stem Cell-Specific Targeting Agent

Yuchae Jung, Heejoo Park, Huiyuan Zhao, +3

Molecules and Cells

Chemoprevention StrategyHigh-grade GliomasCancer BiologyGliomaTumor Biology +18

Molecular insights into PEBP2/CBF beta-SMMHC associated acute leukemia revealed from the structure of PEBP2/CBF beta.

Milton H. Werner, Michael Goger, Vineet Gupta, +3

Nature Structural Biology

Hematological MalignancyCancer ResearchPebp2/cbf BetaPebp2/cbf Beta-smmhcMedicine +6

Insulin‐like growth factor binding protein‐3 suppresses vascular endothelial growth factor expression and tumor angiogenesis in head and neck squamous cell carcinoma

Seung‐Hyun Oh, Woo‐Young Kim, Ok‐Hee Lee, +5

Cancer Science

PathologyCancer BiologyTumor BiologyTumor AngiogenesisAngiogenesis +14