Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor

William J. Zacharias, David B. Frank, Jarod A. Zepp, +6

Nature

Regenerative MedicineRegenerationBiologyTissue DevelopmentDevelopmental Biology +8

Distinct Mesenchymal Lineages and Niches Promote Epithelial Self-Renewal and Myofibrogenesis in the Lung

Jarod A. Zepp, William J. Zacharias, David B. Frank, +4

Cell

Epithelial-mesenchymal TransitionDistinct Mesenchymal LineagesLineage PlasticityDevelopmental BiologyCell Lineage +9

A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice

Ying Tian, Ying Liu, Tao Wang, +13

Science Translational Medicine

Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling

Zinan Zhou, Alan T. Tang, Weng-Yew Wong, +13

Nature

Developmental BiologyEpendymaVascular MalformationCerebral Cavernous MalformationsVascular Biology +4

Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation

David B. Frank, Tien Peng, Jarod A. Zepp, +9

Cell Reports

Human distal airways contain a multipotent secretory cell that can regenerate alveoli

Maria C. Basil, Fabian L. Cardenas‐Diaz, Jaymin J. Kathiriya, +25

Nature

Pulmonary SurfactantLung InflammationPhysiologyMultipotent Secretory CellPulmonary Alveolar Proteinosis +8

Defining the role of pulmonary endothelial cell heterogeneity in the response to acute lung injury

Terren K. Niethamer, Collin T. Stabler, John P. Leach, +5

eLife

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunologyPulmonary Endothelial Cells +17

Sustained miRNA delivery from an injectable hydrogel promotes cardiomyocyte proliferation and functional regeneration after ischaemic injury

Leo Wang, Ying Liu, Jennifer Chung, +9

Nature Biomedical Engineering

Regenerative MedicineTissue EngineeringCell-based Drug DeliveryMirna DeliveryEngineering +10

Hedgehog actively maintains adult lung quiescence and regulates repair and regeneration

Tien Peng, David B. Frank, Rachel S. Kadzik, +7

Nature

BiologyRegenerative MedicineAdult Lung QuiescenceDevelopmental BiologyMorphogenesis +5

Genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus

Jarod A. Zepp, Michael P. Morley, Claudia Loebel, +13

Science