Weiguo Chen

Prostaglandins PGE2 and PGI2 promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation

Anna A. Birukova, Tatiana K. Zagranichnaya, Panfeng Fu et al. · Experimental Cell Research · 2007 · 284 citations · Full text

Inflammation, Signal Transduction, Angiogenesis +14

DPP4 inhibition by sitagliptin attenuates LPS-induced lung injury in mice

Takeshi Kawasaki, Weiguo Chen, Yu Maw Htwe et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2018 · 126 citations · Full text

Acute Lung Injury, Inflammatory Lung Disease, Lung Inflammation +20

Peroxynitrite Induces Destruction of the Tetrahydrobiopterin and Heme in Endothelial Nitric Oxide Synthase: Transition from Reversible to Irreversible Enzyme Inhibition

Weiguo Chen, Lawrence J. Druhan, Chun‐An Chen et al. · Biochemistry · 2010 · 108 citations

Peroxynitrite Induces Destruction, Redox Biology, Oxidative Stress +17

Endothelial cell barrier protection by simvastatin: GTPase regulation and NADPH oxidase inhibition

Weiguo Chen, Srikanth Pendyala, Viswanathan Natarajan et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2008 · 98 citations · Full text

Superoxide Generation, Lipid Peroxidation, Nadph Oxidase Inhibition +17

Formation of Protein Tyrosine ortho-Semiquinone Radical and Nitrotyrosine from Cytochrome c-derived Tyrosyl Radical

Yeong-Renn Chen, Chwen Lih Chen, Weiguo Chen et al. · Journal of Biological Chemistry · 2004 · 90 citations · Full text