En Li

DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Masaki Okano, Daphne W. Bell, Daniel A. Haber et al. · Cell · 1999 · 6.1K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +15

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response

Hui Gao, Joshua M. Korn, Stéphane Ferretti et al. · Nature Medicine · 2015 · 1.4K citations

Medicine, Oncology, Pharmacology +12

Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting

Masahiro Kaneda, Masaki Okano, Kenichiro Hata et al. · Nature · 2004 · 1.4K citations

Medicine, Molecular Biology, Molecular Genetics +16

Reversal of Histone Lysine Trimethylation by the JMJD2 Family of Histone Demethylases

Johnathan R. Whetstine, Amanda C. Nottke, Fei Lan et al. · Cell · 2006 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

Jian Feng, Yu Zhou, Susan L. Campbell et al. · Nature Neuroscience · 2010 · 1K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +16