Jiaxuan Chen

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm

Irène Aksoy, Ralf Jauch, Jiaxuan Chen et al. · The EMBO Journal · 2013 · 199 citations · Full text

Natural Sciences, Genetics, Molecular Biology +5

Conversion of Sox17 into a Pluripotency Reprogramming Factor by Reengineering Its Association with Oct4 on DNA

Ralf Jauch, Irène Aksoy, Andrew P. Hutchins et al. · Stem Cells · 2011 · 105 citations · Full text

Sox17ek Proteins, Genetics, Genomic Mechanism +17

Amphiphilic Dendrimer Vectors for RNA Delivery: State-of-the-Art and Future Perspective

Jiaxuan Chen, Dandan Zhu, Xiaoxuan Liu et al. · Accounts of Materials Research · 2022 · 73 citations · Full text

Engineering, Immunology, Molecular Biology +18

Synthesis and use of an amphiphilic dendrimer for siRNA delivery into primary immune cells

Jiaxuan Chen, Aleksandra Ellert‐Miklaszewska, Stefano Garofalo et al. · Nature Protocols · 2020 · 54 citations · Full text

Cell-based Drug Delivery, Nanomedicine, Primary Immune Cells +10

Cargo-selective and adaptive delivery of nucleic acid therapeutics by bola-amphiphilic dendrimers

Jiaxuan Chen, Dandan Zhu, Baoping Lian et al. · Proceedings of the National Academy of Sciences · 2023 · 36 citations · Full text

Engineering, Molecular Biology, Nucleic Acid Delivery +16