Tianqi Wang

Discovery of <i>N</i>1-(4-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-2-yl)amino)phenyl)-<i>N</i>8-hydroxyoctanediamide as a Novel Inhibitor Targeting Cyclin-dependent Kinase 4/9 (CDK4/9) and Histone Deacetlyase1 (HDAC1) against Malignant Cancer

Yongtao Li, Xiaohe Luo, Qingxiang Guo et al. · Journal of Medicinal Chemistry · 2018 · 76 citations · Full text

Novel hybrid molecule overcomes the limited response of solid tumours to HDAC inhibitors via suppressing JAK1-STAT3-BCL2 signalling

Zhi Huang, Wei Zhou, Yongtao Li et al. · Theranostics · 2018 · 64 citations · Full text

Global sensitivity analysis of hepatic venous pressure gradient (HVPG) measurement with a stochastic computational model of the hepatic circulation

Tianqi Wang, Fuyou Liang, Zun-Qiang Zhou et al. · Computers in Biology and Medicine · 2018 · 42 citations

Engineering, Hepatology, Hepatic Circulation +14

Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-κB Ligand (RANKL)—Receptor Activator of Nuclear Factor-κB (RANK) Protein–Protein Interaction by Structure-Based Virtual Screening and Hit Optimization

Min Jiang, Peng Lei, Kai Yang et al. · Journal of Medicinal Chemistry · 2019 · 38 citations · Full text

Drug Target, Sclerostin, Hit Identification +19

A computational model of the hepatic circulation applied to analyze the sensitivity of hepatic venous pressure gradient (HVPG) in liver cirrhosis

Tianqi Wang, Fuyou Liang, Zun-Qiang Zhou et al. · Journal of Biomechanics · 2017 · 35 citations

Engineering, Hepatology, Hepatic Circulation +13