Cardiolipin Remodeling by ALCAT1 Links Oxidative Stress and Mitochondrial Dysfunction to Obesity

Li Jia, Caroline Romestaing, Xianlin Han, +12

Cell Metabolism

ObesityMetabolic SyndromeCardiolipin RemodelingOxysterolMitochondrial Function +9

Inhibition of autophagy abrogates tumour necrosis factor α induced apoptosis in human T‐lymphoblastic leukaemic cells

Li Jia, R. R. Dourmashkin, Paul Allen, +3

British Journal of Haematology

Final analysis of a phase II study of modified FOLFIRINOX in locally advanced and metastatic pancreatic cancer

Stacey Stein, Edward James, Yanhong Deng, +11

British Journal of Cancer

Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I

Lujing Jiang, Xiaojian Yin, Yahui Chen, +8

Theranostics

Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation

Farideh Miraki‐Moud, Fernando Anjos‐Afonso, Katharine Hodby, +12

Proceedings of the National Academy of Sciences

Apaf-1 protein deficiency confers resistance to cytochromec–dependent apoptosis in human leukemic cells

Li Jia, Srinivasa M. Srinivasula, Fengting Liu, +4

Blood

Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma

Tiansuo Zhao, He Ren, Li Jia, +9

Oncotarget

Design, Synthesis, and Biological Evaluation of Isoquinoline-1,3,4-trione Derivatives as Potent Caspase-3 Inhibitors

Yihua Chen, Yahui Zhang, Hua-jie Zhang, +7

Journal of Medicinal Chemistry

Bioorganic ChemistryCell DeathIsoquinoline-1,3,4-trione DerivativesPharmacotherapyPharmaceutical Chemistry +17

PTEN deletion prevents ischemic brain injury by activating the mTOR signaling pathway

Guodong Shi, Yangyang Ouyang, Jinlong Shi, +3

Biochemical and Biophysical Research Communications

Signal TransductionAutophagyCell DeathNeuroprotectionNeuroscience +8

Blocking Autophagy Prevents Bortezomib-Induced NF-κB Activation by Reducing I-κBα Degradation in Lymphoma Cells

Li Jia, Ganga Gopinathan, Johanna T. Sukumar, +1

PLoS ONE

Ubiquitinated ProteinsApoptosisImmune RegulationImmunologyCell Death +16