RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection

Wenhui Hu, Rafal Kaminski, Fan Yang, +9

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyIntegrated Hiv-1 GenomeHuman RetrovirusMultiplex Grnas +14

TALL-1 is a novel member of the TNF family that is down-regulated by mitogens

Hong‐Bing Shu, Wenhui Hu, H.L. Johnson

Journal of Leukocyte Biology

GeneticsImmune RegulationImmunologyPathologyImmunologic Mechanism +20

Elimination of HIV-1 Genomes from Human T-lymphoid Cells by CRISPR/Cas9 Gene Editing

Rafal Kaminski, Yilan Chen, Tracy Fischer, +6

Scientific Reports

In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models

Chaoran Yin, Ting Zhang, Xiying Qu, +12

Molecular Therapy

Tumor Necrosis Factor-related Apoptosis-inducing Ligand Receptors Signal NF-κB and JNK Activation and Apoptosis through Distinct Pathways

Wenhui Hu, H.L. Johnson, Hong‐Bing Shu

Journal of Biological Chemistry

CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs

Yonggang Zhang, Chaoran Yin, Ting Zhang, +8

Scientific Reports

Glia as a Therapeutic Target: Selective Suppression of Human Amyloid-β-Induced Upregulation of Brain Proinflammatory Cytokine Production Attenuates Neurodegeneration

Hantamalala Ralay Ranaivo, Jeffrey M. Craft, Wenhui Hu, +4

Journal of Neuroscience

Inhibition of calcium-independent phospholipase A2 suppresses proliferation and tumorigenicity of ovarian carcinoma cells

Yuanda Song, Palmer Wilkins, Wenhui Hu, +7

Biochemical Journal

Nuclear Factor Kappa B Signaling Initiates Early Differentiation of Neural Stem Cells

Yonggang Zhang, Jianjun Liu, Shaohua Yao, +18

Stem Cells

Adult Stem CellEarly DifferentiationCell DeathCell SpecializationSocial Sciences +24

Epigallocatechin gallate from green tea effectively blocks infection of SARS-CoV-2 and new variants by inhibiting spike binding to ACE2 receptor

Jinbiao Liu, Brittany Bodnar, Fengzhen Meng, +14

Cell & Bioscience