Silibinin Prevents Autophagic Cell Death upon Oxidative Stress in Cortical Neurons and Cerebral Ischemia-Reperfusion Injury

Min Wang, Yujiao Li, Yi Ding, +8

Molecular Neurobiology

Cerebral Ischemia-reperfusion InjuryCell AutophagyCerebral Vascular RegulationCortical NeuronsNeurophysiology +12

Sphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis is involved in liver fibrosis-associated angiogenesis

Le Yang, Shi Yue, Lin Yang, +4

Journal of Hepatology

InflammationFibrosisSignal TransductionHepatologyAngiogenesis +12

Neutrophils undergo switch of apoptosis to NETosis during murine fatty liver injury via S1P receptor 2 signaling

Xinhao Zhao, Le Yang, Na Chang, +4

Cell Death and Disease

Systemic inflammation induces anxiety disorder through CXCL12/CXCR4 pathway

Le Yang, Minghui Wang, Yanyan Guo, +7

Brain Behavior and Immunity

InflammationPsychoneuroimmunologyAutoimmune DiseasePsychiatryImmunology +5

Macrophage Sphingosine 1-Phosphate Receptor 2 Blockade Attenuates Liver Inflammation and Fibrogenesis Triggered by NLRP3 Inflammasome

Lei Hou, Le Yang, Na Chang, +6

Frontiers in Immunology

Cannabinoid Receptor 1 Participates in Liver Inflammation by Promoting M1 Macrophage Polarization via RhoA/NF-κB p65 and ERK1/2 Pathways, Respectively, in Mouse Liver Fibrogenesis

Lei Tian, Weiyang Li, Le Yang, +6

Frontiers in Immunology

Bone Marrow-Derived Mesenchymal Stem Cells Differentiate to Hepatic Myofibroblasts by Transforming Growth Factor-β1 via Sphingosine Kinase/Sphingosine 1-Phosphate (S1P)/S1P Receptor Axis

Le Yang, Na Chang, Xin Liu, +5

American Journal Of Pathology

Regenerative MedicineDevelopmental BiologyGrowth Factor-β1MedicineLiver Physiology +9

Antidepressant Effect of Paeoniflorin Is Through Inhibiting Pyroptosis CASP-11/GSDMD Pathway

Dandan Tian, Min Wang, An Liu, +9

Molecular Neurobiology

Paeoniflorin IsPsychiatryMedicineApoptosisPsychopharmacology +7

Sphingosine 1-Phosphate Receptor 2 and 3 Mediate Bone Marrow-Derived Monocyte/Macrophage Motility in Cholestatic Liver Injury in Mice

Le Yang, Zhen Han, Lei Tian, +4

Scientific Reports

Macrophage Migration Inhibitor Factor Upregulates MCP-1 Expression in an Autocrine Manner in Hepatocytes during Acute Mouse Liver Injury

Jieshi Xie, Le Yang, Lei Tian, +3

Scientific Reports

Liver FibrosisImmunologyPathologyCell DeathP38 Mapk +24