Pi-Pi contacts are an overlooked protein feature relevant to phase separation

Robert M. Vernon, P. Andrew Chong, Brian Tsang, +5

eLife

Protein ChemistryProtein FunctionProtein AssemblyProtein FoldingNatural Sciences +13

Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling

Aashish Manglik, Tae Hun Kim, Matthieu Masureel, +9

Cell

Molecular PharmacologyMolecular PhysiologySignal TransductionStructural InsightsG Protein-coupled Receptor +7

Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation

Tae Hun Kim, Brian Tsang, Robert M. Vernon, +3

Science

Protein AssemblyMolecular RegulationMolecular BiologyMembraneless OrganellesCytoskeleton +18

Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation

Dean P. Staus, Ryan T. Strachan, Aashish Manglik, +15

Nature

Signal TransductionMolecular PhysiologyBiochemistryG Protein-coupled ReceptorMedicine +10

The role of dimer asymmetry and protomer dynamics in enzyme catalysis

Tae Hun Kim, P. Mehrabi, Zhong Ren, +7

Science

The Role of Ligands on the Equilibria Between Functional States of a G Protein-Coupled Receptor

Tae Hun Kim, Ka Young Chung, Aashish Manglik, +6

Journal of the American Chemical Society

Molecular PhysiologySignal TransductionBiochemistryFunctional SelectivityNatural Sciences +12

Interaction hot spots for phase separation revealed by NMR studies of a CAPRIN1 condensed phase

Tae Hun Kim, Brandon J. Payliss, Michael L. Nosella, +4

Proceedings of the National Academy of Sciences

Role of Detergents in Conformational Exchange of a G Protein-coupled Receptor

Ka Young Chung, Tae Hun Kim, Aashish Manglik, +3

Journal of Biological Chemistry

NMR Experiments for Studies of Dilute and Condensed Protein Phases: Application to the Phase-Separating Protein CAPRIN1

Leo Wong, Tae Hun Kim, D.R. Muhandiram, +2

Journal of the American Chemical Society

Significance of chitinase-3-like protein 1 in the pathogenesis of inflammatory diseases and cancer

Ji Eun Yu, In Jun Yeo, Sang‐Bae Han, +7

Experimental & Molecular Medicine