Characterization of GATA3 Mutations in the Hypoparathyroidism, Deafness, and Renal Dysplasia (HDR) Syndrome

M. Andrew Nesbit, Michael R. Bowl, Brian Harding, +12

Journal of Biological Chemistry

Functional characterization of GATA3 mutations causing the hypoparathyroidism-deafness-renal (HDR) dysplasia syndrome: insight into mechanisms of DNA binding by the GATA3 transcription factor

Asif Ali, P. T. Christie, I. V. Grigorieva, +25

Human Molecular Genetics

Developmental BiologyDna BindingGata3 MutationsSplice Site MutationMedicine +11

Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2

I. V. Grigorieva, Samantha Mirczuk, Katherine U. Gaynor, +15

Journal of Clinical Investigation

Parathyroid AbnormalitiesGeneticsParathyroid DiseaseParathyroid GlandGata3-deficient Mice +15

Role of ROS modified human DNA in the pathogenesis and etiology of cancer

Saba Abdi, Asif Ali

Cancer Letters

Human DnaOncogenic AgentMedicinePathologyCancer Biology +4

Glycated human DNA is a preferred antigen for anti-DNA antibodies in diabetic patients

Imran Mustafa, Saheem Ahmad, Kiran Dixit, +3

Diabetes Research and Clinical Practice

Anti-dna AntibodiesDiabetes ManagementAutoimmune DiseaseHuman Leukocyte AntigenPreferred Antigen +10

Functional Analysis of a Novel GATA3 Mutation in a Family with the Hypoparathyroidism, Deafness, and Renal Dysplasia Syndrome

Alireza Zahirieh, M. Andrew Nesbit, Asif Ali, +7

The Journal of Clinical Endocrinology & Metabolism

Methylglyoxal mediated conformational changes in histone H2A—generation of carboxyethylated advanced glycation end products

Abdul Rouf Mir, Moin Uddin, Khursheed Alam, +1

International Journal of Biological Macromolecules

ChromatinBiochemistryNatural SciencesEpigenetic ChangeHistone H2a—generation +8

Subcellular localization of the J-protein Sis1 regulates the heat shock response

Zoë A. Feder, Asif Ali, Abhyudai Singh, +6

The Journal of Cell Biology

Subcellular LocalizationMolecular BiologyCell InteractionCellular Regulatory MechanismChaperones +17

Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates

Asif Ali, Rania Garde, Olivia Schaffer, +9

Nature Cell Biology

Protein FoldingAdaptive PreservationNatural SciencesMolecular BiologyChaperones +5

Azadiradione ameliorates polyglutamine expansion disease in<i>Drosophila</i>by potentiating DNA binding activity of heat shock factor 1

Vinod Kumar Nelson, Asif Ali, Naibedya Dutta, +13

Oncotarget

Molecular RegulationGeneticsMolecular BiologyCell DeathMolecular Genetics +19