Deyu Li

A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy

Jessica L. Wojtaszek, Nimrat Chatterjee, Javaria Najeeb et al. · Cell · 2019 · 199 citations · Full text

Medicine, Oncology, Pharmacology +9

DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro

Ke Bian, Stefan A. P. Lenz, Qi Tang et al. · Nucleic Acids Research · 2019 · 114 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Oncometabolites <scp>d</scp>- and <scp>l</scp>-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions

Fangyi Chen, Ke Bian, Qi Tang et al. · Chemical Research in Toxicology · 2017 · 80 citations · Full text

Life Sciences, Biochemistry, Oncology +16

Mutation of HIV-1 Genomes in a Clinical Population Treated with the Mutagenic Nucleoside KP1461

James I. Mullins, Laura Heath, James P. Hughes et al. · PLoS ONE · 2011 · 77 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer

Bogdan I. Fedeles, Bret Freudenthal, Emily Yau et al. · Proceedings of the National Academy of Sciences · 2015 · 76 citations · Full text

Pharmacy, Genetics, Toxicology +17