Reprogramming of Sertoli cells to fetal-like Leydig cells by <i>Wt1</i> ablation

Lianjun Zhang, Min Chen, Qing Wen, +8

Proceedings of the National Academy of Sciences

AKT is a therapeutic target in myeloproliferative neoplasms

Irum Khan, Zan Huang, Qing Wen, +15

Leukemia

Hematological MalignancyMedicineImmunologyOncologyCancer Research +1

The Heat-Induced Reversible Change in the Blood-Testis Barrier (BTB) Is Regulated by the Androgen Receptor (AR) via the Partitioning-Defective Protein (Par) Polarity Complex in the Mouse1

Xixia Li, Su‐Ren Chen, Bin Shen, +9

Biology of Reproduction

SpermatogenesisAndrogen ReceptorMolecular RegulationReproductive BiologyCellular Physiology +26

Wt1 dictates the fate of fetal and adult Leydig cells during development in the mouse testis

Qing Wen, Qiaosong Zheng, Xixia Li, +4

American Journal of Physiology-Endocrinology and Metabolism

SpermatogenesisGeneticsReproductive BiologyEmbryologyWt1 Gene +17

Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testis

Qing Wen, Nan Li, Xiang Xiao, +8

Cell Death and Disease

Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development

Qing Wen, Yuqian Wang, Ji‐Xin Tang, +2

PLoS ONE

SpermatogenesisFetal Testis DevelopmentGeneticsReproductive BiologyTestis Cords +19

Dynein 1 supports spermatid transport and spermiation during spermatogenesis in the rat testis

Qing Wen, Elizabeth I. Tang, Wing‐Yee Lui, +4

American Journal of Physiology-Endocrinology and Metabolism

SpermatogenesisFertilityGeneticsMammalian TestisCytoskeleton +19

Impaired histone inheritance promotes tumor progression

Congcong Tian, Jiaqi Zhou, Xinran Li, +17

Nature Communications

<i>Wt1</i> deficiency causes undifferentiated spermatogonia accumulation and meiotic progression disruption in neonatal mice

Qiaosong Zheng, Xiaona Wang, Qing Wen, +8

Reproduction

The Wilms Tumor Gene, Wt1, Maintains Testicular Cord Integrity by Regulating the Expression of Col4a1 and Col4a21

Su‐Ren Chen, Min Chen, Xiaona Wang, +6

Biology of Reproduction

GeneticsCell AdhesionBasal LaminaMolecular GeneticsCellular Physiology +20