Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers

Soo Young Cho, Jun Won Park, Yang Liu, +38

Gastroenterology

Establishment and characterization of metastatic gastric cancer cell lines from murine gastric adenocarcinoma lacking Smad4, p53, and E‐cadherin

Jun Won Park, Dong Min Park, Beom K. Choi, +5

Molecular Carcinogenesis

Smad4 and p53 synergize in suppressing autochthonous intestinal cancer

Jun Won Park, Minjung Seo, Kye Soo Cho, +6

Cancer Medicine

ADRM1 gene amplification is a candidate driver for metastatic gastric cancers

Seok Hoon Jang, Jun Won Park, Hyo Rim Kim, +2

Clinical & Experimental Metastasis

Gastrointestinal OncologyMedicinePathologyCancer GenomicsCancer Biology +9

Comparison of the pathogenesis of SARS-CoV-2 infection in K18-hACE2 mouse and Syrian golden hamster models

Haengdueng Jeong, Youn Woo Lee, In Ho Park, +34

Disease Models & Mechanisms

Lung InflammationViral ImmunityViral PathogenesisImmunologyPathology +14

A synergistic partnership between IL-33/ST2 and Wnt pathway through Bcl-xL drives gastric cancer stemness and metastasis

Jong‐Wan Kwon, Sang‐Hyuk Seok, Somi Kim, +8

Oncogene

Gastrointestinal OncologyMedicineImmunologyCancer BiologyOncology +3

Tcf7l2 in hepatocytes regulates de novo lipogenesis in diet-induced non-alcoholic fatty liver disease in mice

Da Som Lee, Tae Hyeon An, Hyun-Mi Kim, +22

Diabetologia

Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

Jong‐Wan Kwon, Jeong-Seop Oh, Sang Hyeok Seok, +12

Molecular Cancer

Osteopontin depletion decreases inflammation and gastric epithelial proliferation during Helicobacter pylori infection in mice

Jun Won Park, Su Hyung Lee, Du Min Go, +3

Laboratory Investigation

InflammationHelicobacter Pylori InfectionMucosal ImmunologyPathogenesisImmunology +7

In vivo CRISPR–Cas9 knockout screening using quantitative PCR identifies thymosin beta‐4 X‐linked that promotes diffuse‐type gastric cancer metastasis

Hyeok‐Won An, Si‐You Kim, Jong‐Wan Kwon, +4

Molecular Carcinogenesis