Chris Holmes

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

Claire Palles, Jean‐Baptiste Cazier, Kimberley Howarth et al. · Nature Genetics · 2012 · 986 citations · Full text

Markov Chain Monte Carlo Methods and the Label Switching Problem in Bayesian Mixture Modeling

Ajay Jasra, Chris Holmes, David A. Stephens · Statistical Science · 2005 · 674 citations · Full text

Bayesian Statistic, Engineering, Markov Chain Monte Carlo +16

QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data

Stefano Colella, Christopher Yau, Jennifer M. Taylor et al. · Nucleic Acids Research · 2007 · 617 citations · Full text

Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study

Amitava Banerjee, Laura Pasea, Steve Harris et al. · The Lancet · 2020 · 535 citations · Full text

Machine learning and artificial intelligence research for patient benefit: 20 critical questions on transparency, replicability, ethics, and effectiveness

Sebastian J. Vollmer, Bilal A. Mateen, Gergő Bohner et al. · BMJ · 2020 · 457 citations · Full text

Artificial Intelligence, Machine Learning, Interdisciplinary Groups +21