Xiaohu Zhang

RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription

Laura Baranello, Damian Wójtowicz, Kairong Cui et al. · Cell · 2016 · 293 citations · Full text

Chromatin, Transcriptional Regulation, Natural Sciences +8

Early glycolytic reprogramming controls microglial inflammatory activation

Junjie Cheng, Rong Zhang, Zhirou Xu et al. · Journal of Neuroinflammation · 2021 · 229 citations · Full text

Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature

George J. Klarmann, Elaine M. Hurt, Lesley Mathews et al. · Clinical & Experimental Metastasis · 2009 · 220 citations · Full text

Lineage Plasticity, Tumor Heterogeneity, Medicine +8

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

Anish Thomas, Nobuyuki Takahashi, Vinodh N. Rajapakse et al. · Cancer Cell · 2021 · 172 citations · Full text

Oncology, Engineering, High Replication Stress +11

Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis

Jue Hou, Jie Ju, Zili Zhang et al. · Cell Death and Disease · 2019 · 112 citations · Full text