Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in HER2-Positive Metastatic Breast Cancer Previously Treated With ≥ 2 HER2-Directed Regimens: Phase III NALA Trial

Cristina Saura, Mafalda Oliveira, Yin‐Hsun Feng, +32

Journal of Clinical Oncology

Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial

Miguel Martín, Frankie A. Holmes, Bent Ejlertsen, +617

The Lancet Oncology

5-Year AnalysisBreast OncologyOncologyHealth SciencesClinical Trials +8

Induction of Long-term Glycemic Control in Newly Diagnosed Type 2 Diabetic Patients Is Associated With Improvement of β-Cell Function

Yanbing Li, Wen Xu, Zhihong Liao, +5

Diabetes Care

Liraglutide, Sitagliptin, and Insulin Glargine Added to Metformin: The Effect on Body Weight and Intrahepatic Lipid in Patients With Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver Disease

Jinhua Yan, Bin Yao, Hongyu Kuang, +18

Hepatology

International, Randomized, Placebo-Controlled, Double-Blind Phase III Study of Motesanib Plus Carboplatin/Paclitaxel in Patients With Advanced Nonsquamous Non–Small-Cell Lung Cancer: MONET1

Giorgio V. Scagliotti, Ihor Vynnychenko, Keunchil Park, +15

Journal of Clinical Oncology

Prognostic influence of metformin as first‐line chemotherapy for advanced nonsmall cell lung cancer in patients with type 2 diabetes

Benxu Tan, W. Yao, Jun Ge, +11

Cancer

Randomized Phase I Trial of Recombinant Human Keratinocyte Growth Factor Plus Chemotherapy: Potential Role as Mucosal Protectant

Neal J. Meropol, Robert A. Somer, John Gutheil, +9

Journal of Clinical Oncology

Safety Monitoring in Clinical Trials

Bin Yao, Li Zhu, Qi Jiang, +1

Pharmaceutics

Safety ScienceSafety MonitoringBayesian FrameworkClinical TrialsDrug Monitoring +16

A group sequential Holm procedure with multiple primary endpoints

Yining Ye, Li Ai, Lingyun Liu, +1

Statistics in Medicine

Marine HydrodynamicsWeighted Holm ProcedureEngineeringMultiple Primary EndpointsSoftware Testing +3

The mitochondrial protease LONP1 maintains oocyte development and survival by suppressing nuclear translocation of AIFM1 in mammals

Xiaoqiang Sheng, Chuanming Liu, Guijun Yan, +19

EBioMedicine