Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

Katrin D. Mayer-Barber, Bruno B. Andrade, Sandra D. Oland, +16

Nature

Pulmonary TuberculosisAutoimmune DiseaseTuberculosis PreventionImmunologyAntiviral Response +8

PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis

Ray Y. Chen, Lori E. Dodd, Myungsun Lee, +22

Science Translational Medicine

Treatment OutcomeOncologic ImagingTuberculosis PreventionSurrogate EndpointsDiagnostic Imaging +16

Glucose Suppresses Superoxide Generation in Metabolically Responsive Pancreatic β Cells

Geert A. Martens, Ying Cai, Simon A. Hinke, +3

Journal of Biological Chemistry

Lipid PeroxidationMetabolic RemodelingReactive Oxygen SpeciesRedox BiologyInsulin Signaling +17

Linezolid Trough Concentrations Correlate with Mitochondrial Toxicity-Related Adverse Events in the Treatment of Chronic Extensively Drug-Resistant Tuberculosis

Taeksun Song, Myungsun Lee, Han-Seung Jeon, +13

EBioMedicine

Differential Virulence and Disease Progression following Mycobacterium tuberculosis Complex Infection of the Common Marmoset (Callithrix jacchus)

Laura E. Via, Daniel Schimel, Philana Ling Lin, +17

Infection and Immunity

Pathogenic MicrobiologyDisease ProgressionPathologyCommon MarmosetBacterial Pathogenesis +17

Infection Dynamics and Response to Chemotherapy in a Rabbit Model of Tuberculosis using [ ¹⁸ F]2-Fluoro-Deoxy- <scp>d</scp> -Glucose Positron Emission Tomography and Computed Tomography

Laura E. Via, Dan Schimel, Véronique Dartois, +10

Antimicrobial Agents and Chemotherapy

Neurogenin 3+ cells contribute to β-cell neogenesis and proliferation in injured adult mouse pancreas

Mark Van de Casteele, G. Leuckx, Luc Baeyens, +13

Cell Death and Disease

Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation

Ying Cai, Geert A. Martens, Simon A. Hinke, +3

Free Radical Biology and Medicine

Reductive StressSignal TransductionMitochondrial FunctionBiochemistryPhysiology +10

Impact of Diabetes and Smoking on Mortality in Tuberculosis

George Reed, Hongjo Choi, So Young Lee, +13

PLoS ONE

Efficacy and Safety of Metronidazole for Pulmonary Multidrug-Resistant Tuberculosis

Matthew Carroll, Doosoo Jeon, James M. Mountz, +21

Antimicrobial Agents and Chemotherapy

Peripheral NeuropathyPulmonary TuberculosisAntibioticsTuberculosis PreventionPharmacology +10