Yi‐An Chen

Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription

Yanfen Zhu, Amit D. Gujar, Chee‐Hong Wong et al. · Cancer Cell · 2021 · 289 citations · Full text

Medicine, Cancer Biology, Genetics +15

Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway

Yi‐An Chen, Yiling Shen, Hsuan-Yu Hsia et al. · Nature Structural & Molecular Biology · 2017 · 161 citations

Life Sciences, Genetics, Molecular Biology +5

Defining the Ability of Cyclophosphamide Preconditioning to Enhance the Antigen-specific CD8+ T-cell Response to Peptide Vaccination: Creation of a Beneficial Host Microenvironment Involving Type I IFNs and Myeloid Cells

Mohamed L. Salem, Andre N. Kadima, Sabry El-Naggar et al. · Journal of Immunotherapy · 2006 · 118 citations

Life Sciences, Immunology, Pharmacology +17

The TLR3 agonist poly(I:C) targets CD8+ T cells and augments their antigen-specific responses upon their adoptive transfer into naïve recipient mice

Mohamed L. Salem, C. Marcela Díaz‐Montero, Sabry El-Naggar et al. · Vaccine · 2008 · 82 citations

Life Sciences, Immunology, Adaptive Immunity +14

Cyclophosphamide Induces Dynamic Alterations in the Host Microenvironments Resulting in a Flt3 Ligand-Dependent Expansion of Dendritic Cells

Mohamed L. Salem, Amir A. Al-Khami, Sabry El-Naggar et al. · The Journal of Immunology · 2010 · 63 citations · Full text

Life Sciences, Cell Biology, Immunology +13