<i>Propionibacterium acnes</i> induces intervertebral disc degeneration by promoting nucleus pulposus cell apoptosis via the TLR2/JNK/mitochondrial-mediated pathway

Yazhou Lin, Yucheng Jiao, Ye Yuan, +6

Emerging Microbes & Infections

MitophagyApoptosisImmunologyMolecular BiologyCell Death +18

Four-octyl itaconate activates Nrf2 cascade to protect osteoblasts from hydrogen peroxide-induced oxidative injury

Yuehuan Zheng, Zhe Chen, Chang She, +6

Cell Death and Disease

Correlation between the fatty infiltration of paraspinal muscles and disc degeneration and the underlying mechanism

Liqiang Shi, Bin Yan, Yucheng Jiao, +4

BMC Musculoskeletal Disorders

Association between chronic inflammation and latent infection of Propionibacterium acnes in non-pyogenic degenerated intervertebral discs: a pilot study

Ye Yuan, Yong Chen, Zezhu Zhou, +7

European Spine Journal

InflammationBacterial InfectionsIntervertebral DiscPathogenesisImmunology +5

<i>Propionibacterium acnes</i> Induces Intervertebral Disc Degeneration by Promoting iNOS/NO and COX‐2/PGE₂ Activation via the ROS‐Dependent NF‐<i>κ</i>B Pathway

Yazhou Lin, Guoqing Tang, Yucheng Jiao, +7

Oxidative Medicine and Cellular Longevity

Histological Identification of<i>Propionibacterium acnes</i>in Nonpyogenic Degenerated Intervertebral Discs

Ye Yuan, Zezhu Zhou, Yucheng Jiao, +6

BioMed Research International

Acrolein Contributes to the Neuropathic Pain and Neuron Damage after Ischemic–Reperfusion Spinal Cord Injury

Yazhou Lin, Zhe Chen, Jonathan Tang, +2

Neuroscience

InflammationNeuron DamageSpinal Cord InjuryPain MedicineMedicine +9

Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson’s disease: implication of acrolein and TRPA1

Liangqin Shi, Yazhou Lin, Yucheng Jiao, +4

Translational Neurodegeneration

Effect of lentivirus-mediated survivin transfection on the morphology and apoptosis of nucleus pulposus cells derived from degenerative human disc in vitro

Xuexiao Ma, Yazhou Lin, Kun Yang, +3

International Journal of Molecular Medicine

Intervertebral DiscApoptosisPathologyCell DeathRegenerative Medicine +15

Propionibacterium acnes induces discogenic low back pain via stimulating nucleus pulposus cells to secrete pro-algesic factor of IL-8/CINC-1 through TLR2–NF-κB p65 pathway

Yucheng Jiao, Ye Yuan, Yazhou Lin, +8

Journal of Molecular Medicine

InflammationPain SyndromePain DisordersHealth SciencesNucleus Pulposus Cells +10