Chao Zhang

USP14 promotes tryptophan metabolism and immune suppression by stabilizing IDO1 in colorectal cancer

Dongni Shi, Xianqiu Wu, Yunting Jian et al. · Nature Communications · 2022 · 181 citations · Full text

Tryptophan Metabolism, Indoleamine 2,3, Cancer Immunosurveillance +15

NADP+ is an endogenous PARP inhibitor in DNA damage response and tumor suppression

Chunjing Bian, Chao Zhang, Tao Luo et al. · Nature Communications · 2019 · 61 citations · Full text

Structure-Enabled Discovery of Novel Macrocyclic Inhibitors Targeting Glutaminase 1 Allosteric Binding Site

Xi Xu, Jubo Wang, Min Wang et al. · Journal of Medicinal Chemistry · 2021 · 48 citations · Full text

Piperlongumine Inhibits Akt Phosphorylation to Reverse Resistance to Cisplatin in Human Non-Small Cell Lung Cancer Cells via ROS Regulation

Chao Zhang, Lianjun He, Yi‐Bao Zhu et al. · Frontiers in Pharmacology · 2019 · 36 citations · Full text

Nrf2 is a key factor in the reversal effect of curcumin on multidrug resistance in the HCT‑8/5‑Fu human colorectal cancer cell line

Chao Zhang, Lianjun He, Hai‐Zhu Ye et al. · Molecular Medicine Reports · 2018 · 32 citations · Full text

Pathology, Multidrug Resistance, Mdr Modulators +17