Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Seth L. Masters, Aisling Dunne, Shoba Subramanian, +19

Nature Immunology

InflammationAutoimmune DiseaseDiabetesImmune RegulationImmunology +11

Genetic mosaic analysis of a deleterious mitochondrial DNA mutation in<i>Drosophila</i>reveals novel aspects of mitochondrial regulation and function

Zhe Chen, Yun Qi, Stephanie French, +4

Molecular Biology of the Cell

GeneticsGenetic Mosaic AnalysisMitochondrial RegulationMolecular BiologyMolecular Genetics +18

Slow skeletal muscle myosin-binding protein-C (MyBPC1) mediates recruitment of muscle-type creatine kinase (CK) to myosin

Zhe Chen, Tong‐Jin Zhao, Jie Li, +4

Biochemical Journal

Muscle FunctionHigh Energy FluxesMuscle-type Creatine KinaseCytoskeletonMechanotransduction +15

Heterosis in Early Maize Ear Inflorescence Development: A Genome-Wide Transcription Analysis for Two Maize Inbred Lines and Their Hybrid

Haiping Ding, Cheng Qin, Xirong Luo, +10

International Journal of Molecular Sciences

BiologyPlant GeneticsDevelopmental BiologyFunctional GenomicsMolecular Breeding +13

E2f5 is a versatile transcriptional activator required for spermatogenesis and multiciliated cell differentiation in zebrafish

Haibo Xie, Yunsi Kang, Shuo Wang, +4

PLoS Genetics

SpermatogenesisGeneticsCell DifferentiationReproductive BiologyZebrafish E2f5 +18

Molecular mechanisms of enhancing porcine granulosa cell proliferation and function by treatment in vitro with anti-inhibin alpha subunit antibody

Liuping Cai, Aidong Sun, Hui Li, +5

Reproductive Biology and Endocrinology

Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, +6

International Journal of Molecular Medicine

Exogenous SpermineRenal PathologyRenal InflammationDiabetic Kidney InjuryOxidative Stress +22

Genome expression profile analysis of the maize sheath in response to inoculation to R. solani

Jian Gao, Zhe Chen, Mao Luo, +9

Molecular Biology Reports

Plant GeneticsGeneticsPlant PathologyMolecular GeneticsGenomics +15

Acridone Derivative 8a Induces Oxidative Stress-Mediated Apoptosis in CCRF-CEM Leukemia Cells: Application of Metabolomics in Mechanistic Studies of Antitumor Agents

Yini Wang, Dan Gao, Zhe Chen, +6

PLoS ONE

Chemoprevention StrategyLipid PeroxidationApoptosisCell DeathPharmacotherapy +21

The cytoplasmic tail of rhodopsin triggers rapid rod degeneration in kinesin-2 mutants

Feng Dong, Zhe Chen, Kuang Yang, +5

Journal of Biological Chemistry

Molecular BiologyCytoskeletonCellular PhysiologyGanglion CellRetina +18