Mutations in SUFU predispose to medulloblastoma

Michael D. Taylor, Ling Liu, Corey Raffel, +15

Nature Genetics

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The Kinesin Protein Kif7 Is a Critical Regulator of Gli Transcription Factors in Mammalian Hedgehog Signaling

Helen Oi-Lam Cheung, Xiaoyun Zhang, Ana Ribeiro, +6

Science Signaling

Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms

Paul C. Barnfield, Xiaoyun Zhang, Vijitha Thanabalasingham, +2

Differentiation

Transcriptional RegulationSystems BiologySignal TransductionSignaling PathwayMultiple Mechanisms +8

Formation of Proximal and Anterior Limb Skeleton Requires Early Function of Irx3 and Irx5 and Is Negatively Regulated by Shh Signaling

Danyi Li, Rui Sakuma, N Alizadeh Vakili, +6

Developmental Cell

MechanobiologyMusculoskeletal ResearchDevelopmental BiologySignal TransductionBone Morphogenic Protein +7

Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches

Ji‐Eun Kim, Lijiang Fei, Wen-Chi Yin, +12

Nature Communications

GeneticsGastroenterologyCellular PhysiologyTissue DevelopmentSignaling Pathway +20

The Iroquois homeobox gene, Irx5, is required for retinal cone bipolar cell development

Chi Cheng, Robert L. Chow, Mélanie Lebel, +9

Developmental Biology

Photoreceptor CellDevelopmental BiologyRetinaOphthalmologyMedicine +6

Mice Deficient in MyD88 Develop a Th2-Dominant Response and Severe Pathology in the Upper Genital Tract following <i>Chlamydia</i> <i> muridarum</i> Infection

Lili Chen, Lei Lei, Xiaotong Chang, +6

The Journal of Immunology

Innate Immune SystemImmunologyPathologyMyd88 Ko MiceInnate Immunity +15

Failure of a medulloblastoma-derived mutant of SUFU to suppress WNT signaling

Michael D. Taylor, Xiaoyun Zhang, Ling Liu, +6

Oncogene

Developmental BiologySignaling PathwayMedulloblastoma-derived MutantGene ExpressionMedicine +3

Mice with a Targeted Mutation of <i>Patched2</i> Are Viable but Develop Alopecia and Epidermal Hyperplasia

Erica Nieuwenhuis, Jun Motoyama, Paul C. Barnfield, +5

Molecular and Cellular Biology

GeneticsDermatologyBasal Cell CarcinomaTissue PatterningTumor Biology +14

Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis

Zhu Juan Li, Erica Nieuwenhuis, Weilun Nien, +6

Development

Skin DevelopmentTranscriptional Regulation-Independent FunctionsDevelopmental BiologySignal Transduction +12