Cellular Immune Responses to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection in Senescent BALB/c Mice: CD4⁺T Cells Are Important in Control of SARS-CoV Infection

Jun Chen, Yuk Fai Lau, Elaine W. Lamirande, +4

Journal of Virology

Microbiota-Dependent Activation of an Autoreactive T Cell Receptor Provokes Autoimmunity in an Immunologically Privileged Site

Reiko Horai, Carlos R. Zárate-Bladés, Patrícia Dillenburg-Pilla, +8

Immunity

InflammationAllergyAutoimmune DiseaseT-regulatory CellImmunology +9

Disulfiram/Copper Induces Antitumor Activity against Both Nasopharyngeal Cancer Cells and Cancer-Associated Fibroblasts through ROS/MAPK and Ferroptosis Pathways

Yiqiu Li, Fangfang Chen, Jun Chen, +4

Cancers

SARS-CoV Pathogenesis Is Regulated by a STAT1 Dependent but a Type I, II and III Interferon Receptor Independent Mechanism

Matthew B. Frieman, Jun Chen, Thomas E. Morrison, +8

PLoS Pathogens

InflammationIii InterferonInflammatory Lung DiseaseLung InflammationMedicine +13

The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24

Wai Po Chong, Mary J. Mattapallil, Kumarkrishna Raychaudhuri, +11

Immunity

InflammationCytokineAutoimmune DiseaseAllergyT-regulatory Cell +8

Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14+ monocytes

Ziliang Zhou, Chunliu Huang, Zhechong Zhou, +10

iScience

CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response

Marc Martínez‐Llordella, Jonathan H. Esensten, Samantha L. Bailey-Bucktrout, +7

The Journal of Experimental Medicine

Breakdown of immune privilege and spontaneous autoimmunity in mice expressing a transgenic T cell receptor specific for a retinal autoantigen

Reiko Horai, Phyllis B. Silver, Jun Chen, +12

Journal of Autoimmunity

Immune PrivilegeSpontaneous AutoimmunityAutoimmune DiseaseAllergyT-regulatory Cell +10

MMDB: annotating protein sequences with Entrez's 3D-structure database

Y. Wang, Kenneth J. Addess, Jun Chen, +9

Nucleic Acids Research

Structural BioinformaticsMolecular BiologyAnnotation ServiceBioinformatics DatabaseProteomics +14

The Living Eye “Disarms” Uncommitted Autoreactive T Cells by Converting Them to Foxp3+ Regulatory Cells following Local Antigen Recognition

Ru Zhou, Reiko Horai, Phyllis B. Silver, +7

The Journal of Immunology