Rui Li

ecDNA hubs drive cooperative intermolecular oncogene expression

King L. Hung, Kathryn E. Yost, Liangqi Xie et al. · Nature · 2021 · 337 citations · Full text

Medicine, Genetics, Molecular Biology +17

Synthesis and biological evaluation of 4-(1,2,3-triazol-1-yl)coumarin derivatives as potential antitumor agents

Wenjuan Zhang, Zhi Li, Meng Zhou et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 150 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8

Enhancing transcription–replication conflict targets ecDNA-positive cancers

Jun Tang, Natasha E. Weiser, Guiping Wang et al. · Nature · 2024 · 88 citations · Full text

Medicine, Cancer Biology, Oncology +17

Coordinated inheritance of extrachromosomal DNAs in cancer cells

King L. Hung, Matthew G. Jones, Ivy Tsz-Lo Wong et al. · Nature · 2024 · 77 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Killing colon cancer cells through PCD pathways by a novel hyaluronic acid-modified shell-core nanoparticle loaded with RIP3 in combination with chloroquine

Xueyan Hou, Chengli Yang, Lijing Zhang et al. · Biomaterials · 2017 · 71 citations

Pharmacy, Oncology, Pharmacology +16