A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

Damien Chaussabel, Charles T. Quinn, Jing Shen, +26

Immunity

GeneticsGenetic EpidemiologyMultiomicsGenome-wide Association StudyBiostatistics +14

A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate

Phillip T. Newton, Lei Li, Baoyi Zhou, +23

Nature

BiologyEmbryonic Stem CellCell LineageDevelopmental BiologyClonality Reveals +11

Targeted deletion of Atg5 in chondrocytes promotes age-related osteoarthritis

Thibault Bouderlique, Karuna K Vuppalapati, Phillip T. Newton, +3

Annals of the Rheumatic Diseases

Superficial cells are self‐renewing chondrocyte progenitors, which form the articular cartilage in juvenile mice

Lei Li, Phillip T. Newton, Thibault Bouderlique, +13

The FASEB Journal

Functional Analysis of Host Factors that Mediate the Intracellular Lifestyle of Cryptococcus neoformans

Qing‐Ming Qin, Jijing Luo, Xiaorong Lin, +4

PLoS Pathogens

DysbiosisImmunologyCytoskeletonFunctional AnalysisAutophagy +14

Infiltrating mast cells enhance prostate cancer invasion<i>via</i>altering LncRNA-HOTAIR/PRC2-androgen receptor (AR)-MMP9 signals and increased stem/progenitor cell population

Lei Li, Qiang Dang, Hongjun Xie, +6

Oncotarget

XIST/miR‐376c‐5p/OPN axis modulates the influence of proinflammatory M1 macrophages on osteoarthritis chondrocyte apoptosis

Lei Li, Guohua Lv, Bing Wang, +1

Journal of Cellular Physiology

Secondary ossification center induces and protects growth plate structure

Meng Xie, Pavel Gol’din, Anna Nele Herdina, +28

eLife

Regenerative MedicineMechanobiologyDevelopmental BiologyEngineeringBone Morphogenic Protein +13

Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model

Ao Duan, Kai Shen, Beichen Li, +16

Stem Cell Research & Therapy

Structure, Mechanism, and Conformational Dynamics of <i>O</i>-Acetylserine Sulfhydrylase from <i>Salmonella typhimurium</i>:  Comparison of A and B Isozymes

Arundhati Chattopadhyay, Markus Meier, Sergei Ivaninskii, +8

Biochemistry