Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells

Yunlong Cao, Bin Su, Xianghua Guo, +29

Cell

Viral DiagnosticsPotent Neutralizing AntibodiesImmunologyHigh-throughput Single-cell SequencingHumoral Response +6

A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues

Dominik Saul, Robyn Laura Kosinsky, Elizabeth J. Atkinson, +16

Nature Communications

Stoichiometry controls activity of phase-separated clusters of actin signaling proteins

Lindsay B. Case, Xu Zhang, Jonathon A. Ditlev, +1

Science

Proteinlipid InteractionProtein AssemblyMolecular BiologyCytoskeletonProtein Phase Separation +16

The senescence-associated secretome as an indicator of age and medical risk

Marissa J. Schafer, Xu Zhang, Amanika Kumar, +15

JCI Insight

AgingSenescence-associated SecretomeImmunologyGynecologyPathology +21

Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses

Xiancai Ma, Fan Zou, Fei Yu, +22

Immunity

VaccinationReceptor Binding DomainCross-protectionVaccine DevelopmentImmunology +6

The draft genome of the parasitic nematode Trichinella spiralis

Makedonka Mitreva, Douglas P. Jasmer, Dante S. Zarlenga, +18

Nature Genetics

Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis

Yong‐Jie Zhang, Tania F. Gendron, Mark Ebbert, +20

Nature Medicine

Amyotrophic Lateral SclerosisAlzheimer's DiseaseDementiaProtein TranslationStress Granule Dynamics +7

Neutrophil-related factors as biomarkers in EAE and MS

Julie M. Rumble, Amanda K. Huber, Gurumoorthy Krishnamoorthy, +5

The Journal of Experimental Medicine

Safety and immunogenicity of a recombinant adenovirus type-5 vector-based Ebola vaccine in healthy adults in Sierra Leone: a single-centre, randomised, double-blind, placebo-controlled, phase 2 trial

Fengcai Zhu, Alie Wurie, Lihua Hou, +17

The Lancet

VaccinationVaccine SafetyVaccine DevelopmentVaccine EfficacySierra Leone +4

Characterization of cellular senescence in aging skeletal muscle

Xu Zhang, Leena Habiballa, Zaira Aversa, +21

Nature Aging

MechanobiologyAgingSkeletal MuscleSarcopeniaLongevity +4