Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer’s disease model

Li Zhong, Ying Xu, Rengong Zhuo, +20

Nature Communications

Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)

Li Zhong, Zongqi Wang, Daxin Wang, +11

Molecular Neurodegeneration

TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration

Li Zhong, Xuan Sheng, Wanbing Wang, +15

Immunity

Complement SystemSignal TransductionMedicineNeurotransmitterImmunology +7

Vimentin-expressing proximal reactive astrocytes correlate with migration rather than proliferation following focal brain injury

Kai Wang, Lane K. Bekar, Kendra L. Furber, +1

Brain Research

Traumatic Brain InjuryMolecular NeuroscienceMedicineBrain-immune InteractionNeuroprotection +10

An Unconventional Hydrofullerene C₆₆H₄ with Symmetric Heptagons Retrieved in Low-Pressure Combustion

Han‐Rui Tian, Miaomiao Chen, Kai Wang, +9

Journal of the American Chemical Society

PPARγ coactivator-1α (PGC-1α) protects neuroblastoma cells against amyloid-beta (Aβ) induced cell death and neuroinflammation via NF-κB pathway

Yuqin Zhang, Changchun Chen, Yanliu Jiang, +3

BMC Neuroscience

Molybdenum-Catalyzed Intermolecular Deoxygenative Cross-Coupling Reactions of 1,2-Diketones with α-Ketoamides

Yuanqing Dong, Kai Wang, Chun‐Xiang Zhuo

ACS Catalysis

Cross-coupling ReactionEngineeringNatural SciencesDiversity-oriented SynthesisCommercial Mo-catalyst +8

INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model

Akihiro Iguchi, Sho Takatori, Shingo Kimura, +13

iScience

Oral Delivery of Bavachinin-Loaded PEG-PLGA Nanoparticles for Asthma Treatment in a Murine Model

Kai Wang, Yupeng Feng, Shuang Li, +5

Journal of Biomedical Nanotechnology

NanoparticlesEngineeringBavachinin-loaded Peg5000-plga NpsImmunologyBavachinin-loaded Peg-plga Nanoparticles +15

Knockdown of TLR4 Represses the Paraquat-Induced Neuroinflammation and Microglial M1 Polarization

Min Huang, Yingying Li, Tian Tian, +4

Neurotoxicity Research

InflammationToll-like ReceptorsMicroglial M1 PolarizationCytokineMedicine +7