Jie Zhang

Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence

Hei‐Man Chow, Meng Shi, Aifang Cheng et al. · Nature Neuroscience · 2019 · 165 citations

Lifespan Extension, Aging, Geriatrics +10

Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance

Lige Leng, Ziqi Yuan, Rui‐Yuan Pan et al. · Nature Metabolism · 2022 · 156 citations

Inflammation, Neurodegenerative Diseases, Microglial Hexokinase 2 +10

Lactate Deficit in an Alzheimer Disease Mouse Model: The Relationship With Neuronal Damage

Mao Zhang, Xiaofang Cheng, Ruozhi Dang et al. · Journal of Neuropathology & Experimental Neurology · 2018 · 104 citations

Cerebral Mct1, Alzheimer's Disease, Dementia +15

CDK5 activator protein p25 preferentially binds and activates GSK3β

Hei‐Man Chow, Dong Guo, Jiechao Zhou et al. · Proceedings of the National Academy of Sciences · 2014 · 75 citations · Full text

ACSS2-dependent histone acetylation improves cognition in mouse model of Alzheimer’s disease

Yingbin Lin, Anlan Lin, Lili Cai et al. · Molecular Neurodegeneration · 2023 · 63 citations · Full text