Chang Li

In vivo HSPC gene therapy with base editors allows for efficient reactivation of fetal γ-globin in β-YAC mice

Chang Li, Aphrodite Georgakopoulou, Arpit Mishra et al. · Blood Advances · 2021 · 86 citations · Full text

In Vivo Gene Therapy, Genetics, Genomic Mechanism +16

Reactivation of γ-globin in adult β-YAC mice after ex vivo and in vivo hematopoietic stem cell genome editing

Chang Li, Nikoletta Psatha, Pavel Sova et al. · Blood · 2018 · 78 citations · Full text

<i>In vivo</i> HSC prime editing rescues Sickle Cell Disease in a mouse model

Chang Li, Aphrodite Georgakopoulou, Gregory A. Newby et al. · Blood · 2023 · 68 citations · Full text

In Vivo HSC Gene Therapy Using a Bi-modular HDAd5/35++ Vector Cures Sickle Cell Disease in a Mouse Model

Chang Li, Hongjie Wang, Aphrodite Georgakopoulou et al. · Molecular Therapy · 2020 · 67 citations · Full text

Targeted Integration and High-Level Transgene Expression in AAVS1 Transgenic Mice after In Vivo HSC Transduction with HDAd5/35++ Vectors

Chang Li, Arpit Mishra, Sucheol Gil et al. · Molecular Therapy · 2019 · 40 citations · Full text