Aberrant translation regulated by METTL1/WDR4‐mediated tRNA N7‐methylguanosine modification drives head and neck squamous cell carcinoma progression

Jie Chen, Kang Li, Jianwen Chen, +12

Cancer Communications

ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer

Jiehui Deng, Aatish Thennavan, Igor Dolgalev, +35

Nature Cancer

MedicineImmunologyTumor ImmunityUlk1 Inhibition OvercomesAntigen Presentation +7

Gankyrin promotes tumor growth and metastasis through activation of IL-6/STAT3 signaling in human cholangiocarcinoma

Tongsen Zheng, Xuehui Hong, Jiabei Wang, +17

Hepatology

Spatial single-cell protein landscape reveals vimentinhigh macrophages as immune-suppressive in the microenvironment of hepatocellular carcinoma

Xinyao Qiu, Tao Zhou, Shuai Li, +9

Nature Cancer

Hepatocellular CarcinomaMedicineLiver PhysiologyImmunologyBiological Microenvironments +8

Metabolic reprogramming driven by METTL1-mediated tRNA m7G modification promotes acquired anlotinib resistance in oral squamous cell carcinoma

Jie Chen, Qimin Zhou, Shuai Li, +5

Translational research

Oncogenic AgentMedicineCancer GenomicsTumor SuppressorSystems Biology +5

Epigenetic CRISPR Screens Identify <i>Npm1</i> as a Therapeutic Vulnerability in Non–Small Cell Lung Cancer

Fei Li, Wai‐Lung Ng, Troy A. Luster, +27

Cancer Research

Disruption of RBMS3 suppresses PD-L1 and enhances antitumor immune activities and therapeutic effects of auranofin against triple-negative breast cancer

Yuting Zhou, Zhongping Liang, Yingjie Xia, +7

Chemico-Biological Interactions

Cancer ImmunosurveillanceMedicineImmune ActivitiesImmunologyTumor Immunity +11

N7-methylguanosine-related lncRNAs: Distinction between hot and cold tumors and construction of predictive models in colon adenocarcinoma

Zhichao Cheng, Jiaqi Wang, Yixin Xu, +6

Frontiers in Oncology

Structure-guided discovery of bile acid derivatives for treating liver diseases without causing itch

Jun J. Yang, Tianjun Zhao, Junping Fan, +12

Cell

HepatologyBiochemistryBiliary TractMedicineLiver Physiology +9

METTL3 suppresses anlotinib sensitivity by regulating m6A modification of FGFR3 in oral squamous cell carcinoma

Jie Chen, Shuai Li, Zhexun Huang, +3

Cancer Cell International