Xia Chen

Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury

Kiyoshi Mori, H. Thomas Lee, Dana Rapoport et al. · Journal of Clinical Investigation · 2005 · 916 citations · Full text

The BACE1 inhibitor verubecestat (MK-8931) reduces CNS β-amyloid in animal models and in Alzheimer’s disease patients

Matthew Kennedy, Andrew W. Stamford, Xia Chen et al. · Science Translational Medicine · 2016 · 407 citations

Glucose Homeostasis, Bace1 Inhibitor Verubecestat, Enzyme 1 +20

Gut dysbiosis induces the development of pre-eclampsia through bacterial translocation

Xia Chen, Pan Li, Mian Liu et al. · Gut · 2020 · 328 citations · Full text

Resetting histone modifications during human parental-to-zygotic transition

Weikun Xia, Jiawei Xu, Guang Yu et al. · Science · 2019 · 270 citations · Full text

Histone Modifications, Chromatin, Developmental Biology +14

Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer

Yadong Xie, Yifan Zhao, Lei Shi et al. · Journal of Clinical Investigation · 2020 · 201 citations · Full text

Intestinal Inflammation, Gut Epithelial Tsc1/mtor, Apoptosis +22