The role of genetics in Parkinson’s disease: a large cohort study in Chinese mainland population

Yuwen Zhao, Lixia Qin, Hongxu Pan, +58

Brain

GeneticsGenetic EpidemiologyPathologyLarge Cohort StudyDisease Gene Identification +16

Heparin prevents caspase-11-dependent septic lethality independent of anticoagulant properties

Yiting Tang, Xiangyu Wang, Zhaozheng Li, +13

Immunity

InflammationThrombosisLiver PhysiologyHematologyCaspase-11-dependent Septic Lethality +9

WWP2 regulates proliferation of gastric cancer cells in a PTEN-dependent manner

Ke Wang, Jun Liu, Xinhui Zhao, +11

Biochemical and Biophysical Research Communications

Cancer ResearchGastric Cancer CellsSignal TransductionSignaling PathwayCell Regulation +8

USP5 Sustains the Proliferation of Glioblastoma Through Stabilization of CyclinD1

Gen Li, Tianquan Yang, Yanling Chen, +12

Frontiers in Pharmacology

The steady-state level of CDK4 protein is regulated by antagonistic actions between PAQR4 and SKP2 and involved in tumorigenesis

Lin Wang, Rui Zhang, Xue You, +6

Journal of Molecular Cell Biology

Cdk4 ProteinCell ProliferationCell CycleTumor BiologyAntagonistic Actions +15

Gene4PD: A Comprehensive Genetic Database of Parkinson’s Disease

Bin Li, Guihu Zhao, Qiao Zhou, +19

Frontiers in Neuroscience

Systematically analyzing rare variants of autosomal-dominant genes for sporadic Parkinson's disease in a Chinese cohort

Nannan Yang, Yuwen Zhao, Rui Zhang, +7

Neurobiology of Aging

EngineeringMendelian DisorderChinese CohortGenetic DisorderSporadic Parkinson +9

A small molecule binding HMGB1 inhibits caspase-11-mediated lethality in sepsis

Xiangyu Wang, Zhaozheng Li, Yang Bai, +8

Cell Death and Disease

ApoptosisImmunologyCell DeathPathologyImmunotherapy +14

Inflammatory cytokine‑induced expression of MASTL is involved in hepatocarcinogenesis by regulating cell cycle progression

Liye Cao, Wenjuan Li, Jihong Yang, +9

Oncology Letters

Critical role of ROCK1 in AD pathogenesis via controlling lysosomal biogenesis and acidification

Chenghuan Song, Wan‐Ying Huang, Pingao Zhang, +10

Translational Neurodegeneration