Hong Chen

YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer

Jiangfeng Li, Haiyun Xie, Yufan Ying et al. · Molecular Cancer · 2020 · 379 citations · Full text

Medicine, Cancer Biology, Oncology +17

Trans-nuclease activity of Cas9 activated by DNA or RNA target binding

Jiyun Chen, Ying Chen, Linglong Huang et al. · Nature Biotechnology · 2024 · 73 citations

Life Sciences, Genetics, Molecular Biology +10

Comparison of the yield and purity of plasma exosomes extracted by ultracentrifugation, precipitation, and membrane-based approaches

Weijian Li, Hong Chen, Man-Li Tong et al. · Open Chemistry · 2022 · 54 citations · Full text

Life Sciences, Biochemistry, Cell Biology +13

Downregulation of ribosomal protein S6 inhibits the growth of non-small cell lung cancer by inducing cell cycle arrest, rather than apoptosis

Bojiang Chen, Wen Zhang, Jun Gao et al. · Cancer Letters · 2014 · 46 citations

Life Sciences, Molecular Biology, Oncology +16

Low RNA stability signifies increased post-transcriptional regulation of cell identity genes

Yanqiang Li, Yi Yang, Jie Lv et al. · Nucleic Acids Research · 2023 · 43 citations · Full text

Life Sciences, Genetics, Molecular Biology +16